dsolve

gelwoRx™ Dsolve: the advanced solution for reduced crosslinking in soft caps

The gelwoRx™ Dsolve range has been specially designed to provide advanced solutions for reduced crosslinking of soft gelatin capsules to enable fast shell dissolution and rapid fill release.
Protein crosslinking is the process of joining two or more protein molecules through intermolecular cova­lent bonds, which promotes the formation of macromolecular structures.

Crosslinking is a natural phenomenon in gelatin, by which gelatin molecules link together and dissolve more slowly due to circumstances such as humidity or storage temperature, or the chemical properties of a capsule’s filling. 

gelwoRx™ Dsolve significantly reduces the crosslinking behavior of soft gelatin capsule and boasts superior dissolution performance compared to the gold standard for soft gelatin capsule. Moreover, it guarantees a rapid fill releaseimproved stability, and increased shelf life of the final dosage formulations.  

gelwoRx™ Dsolve B&P

dsolve

Dsolve B (beef hide gelatin) and Dsolve P (pig skin gelatin) exhibit reduced crosslinking and better dissolution performance compared to the gold standard in soft gelatin caps.

Designed for APIs (Rx and OTC) and nutritional supplements

Can be effortlessly introduced into the existing production process.

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gelwoRx™ Dsolve: proven benefits

Lab assistant holding a tube of soft capsules

30% lower crosslinking tendency thanks to the

              gelwoRx™ Dsolve portfolio:

 

Reduced crosslinking of the soft gelatin capsule shell  

                          ↓

Faster capsule dissolution

                          ↓

Rapid & reliable filling release

                          ↓

Improved stability & increased shelf life
          of final dosage formulations

 

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gelwoRx™ Dsolve: Test results show improved performance

Dsolve dissolution capsule

Tests confirmed that gelwoRx™ Dsolve significantly outperforms the standard gelatin for soft gelatin capsules in terms of shell dissolution and fill release in the presence of crosslinkers.